
The PrEP initiative has 3 core components focused on providers, users, and measuring impact. A PrEP steering committee will oversee efforts in these 3 areas:
Improved user knowledge and access
- Broad-based education campaign to reach into heavily impacted communities
- User hotline for information, resources
- Website as “one-stop shop” of local and national resources and information
- Affordability program including navigators to assist potential users with insurance and provider choice, access to co-pay/deductible/payment assistance
- Speakers bureau of PrEP users
- Programs to support PrEP adherence
Increased provider capacity
- Support for public-access PrEP clinics
- Training, resources for providers in diverse fields (primary care, Ob/Gyn, pediatrics, psychiatry)
- Warm line for providers
- Online tools
- Cultural humility training for providers
Tracking PrEP uptake and impact
- Measure PrEP use citywide (including demographics and behavior of PrEP users, duration of use, type of PrEP)
- Track potential negative consequences (e.g., breakthrough infections, resistance, social harms, STIs, difficulty accessing PrEP)
- Track potential benefit (e.g., impact on HIV incidence, access to comprehensive health services for PrEP users)
- Track sexual and injection behaviors over time
- Track PrEP- and HIV-associated stigma
- Measure cost to providers, payers, users
PrEP Committee Resources

Resources for people interested in PrEP
- PrEP Basics Fact Sheet, updated December 2021 – San Francisco Department of Public Health
- Lo Esencial de PrEP, updated December 2021 – San Francisco Department of Public Health
- San Francisco City Clinic – PrEP Information
Resources for PrEP providers
- San Francisco City Clinic PrEP Section
- SFCC PrEP Navigation Services Protocol (v. 12/7/18) – San Francisco City Clinic
- San Francisco Health Network Pre-Exposure Prophylaxis (PrEP) Management Guidelines, June 2016
- *2021* Ask about PrEP: How providers can prescribe PrEP to prevent HIV and reduce health disparities – San Francisco Department of Public Health
- PrEP Navigation Manual: Helping People Access Pre-Exposure Prophylaxis – PleasePrEPMe.org and Project Inform
- Ayudando A Las Personas a Tener Acceso A La Profilaxis Anterior a la Exposición (en Español) – PleasePrEPMe.org and Project Inform
PrEP News & Updates
Latest from PrEP Committee
[New Publication] The case for prescribing PrEP in community mental health settings
Sudler A, Cournos F, Arnold E, Koester K, Riano NS, Dilley J, Liu A, Mangurian C. The case for prescribing PrEP in community mental health settings. Lancet HIV. 2021 Apr;8(4):e237-e244. doi: 10.1016/S2352-3018(20)30273-3. Epub 2021 Jan 22. PMID: 33493438. Abstract Pre-exposure prophylaxis (PrEP) is a biomedical HIV prevention modality that is up to 99% effective in…
Truvada® is going generic on September 30, 2020: Update for San Francisco PrEP Users (updated 10/14)
Where can I learn more?If you or your provider have any questions, please contact San Francisco City Clinic at sfccpatientservices.dph@sfdph.org. For more information on generic medications, the FDA maintains information at its Generic Drug Facts page.
New Resource from SFAF: Which PrEP medication is best for me? Truvada and Descovy Comparison
If you have questions, please contact Janessa Broussard (jbroussard@sfaf.org) Director of Clinical Services, San Francisco AIDS Foundation.
*UPDATED* ‘Dear Colleague’ Letter – SFDPH offering guidance on several topics related to HIV prevention
Click below to download the full *updated* Dear Colleague Letter. Dear Colleague, We’re writing to share with you recommendations on how to incorporate new developments in HIV prevention and care into your practice. The San Francisco Department of Public Health recommends that you: Screen all sexually active MSM, trans women, and trans men who have…