The PrEP initiative has 3 core components focused on providers, users, and measuring impact.
Improved user knowledge and access
- Broad-based education campaign to reach into heavily impacted communities
- User hotline for information, resources
- Website as “one-stop shop” of local and national resources and information
- Affordability program including navigators to assist potential users with insurance and provider choice, access to co-pay/deductible/payment assistance
- Speakers bureau of PrEP users
- Programs to support PrEP adherence
Increased provider capacity
- Support for public-access PrEP clinics
- Training, resources for providers in diverse fields (primary care, Ob/Gyn, pediatrics, psychiatry)
- Warm line for providers
- Online tools
- Cultural humility training for providers
Tracking PrEP uptake and impact
- Measure PrEP use citywide (including demographics and behavior of PrEP users, duration of use, type of PrEP)
- Track potential negative consequences (e.g., breakthrough infections, resistance, social harms, STIs, difficulty accessing PrEP)
- Track potential benefit (e.g., impact on HIV incidence, access to comprehensive health services for PrEP users)
- Track sexual and injection behaviors over time
- Track PrEP- and HIV-associated stigma
- Measure cost to providers, payers, users
PrEP Committee Resources
Resources for individuals interested in PrEP and doxy-PEP
- PrEP Basics Fact Sheet/Lo Esencial de PrEP – by San Francisco Department of Public Health
- Injectable PrEP Basics Fact Sheet/Lo Esencial de la PrEP inyectable — by San Francisco Department of Public Health
- PrEP Options (comparison chart pill & injectable option) – SFAF (English and Spanish)
- List of Clinics in SF Offering Long-Acting Injectable (LAI) for HIV PrEP & Treatment for prevention and treatment, clients they serve, and healthcare coverage they accept
doxy-PEP
- About Doxy-PEP Fact Sheet — San Francisco City Clinic
- Acerca de Doxy-PEP — San Francisco City Clinic
Resources for providers & frontline workers
- Page of resources
- Ask about PrEP: How providers can prescribe PrEP to prevent HIV and reduce health disparities – San Francisco Department of Public Health
- Prescribing oral PrEP Pocket Card – by San Francisco Department of Public Health
- PrEP Navigation Manual: Helping People Access Pre-Exposure Prophylaxis – PleasePrEPMe.org & getSFcba
Injectable PrEP
- Ward 86 Long Acting Pre-Exposure Prophylaxis (PrEP) Guidelines (CAB LA and LEN LA), November 2025
- SFDPH Whole Person Integrated Care (WPIC): Long-Acting Injectable ART & PrEP Protocols, May 2025
- Long-Acting Injectable (LAI) ART & PrEP: The frontline worker’s role in team-based care (English, Spanish) – SF HIV FOG
- Injectable HIV Medications and PrEP – Resources compiled by East Bay Getting to Zero
- Yeztugo Insurance Flowsheet
- Apretude Insurance Flowsheet
PrEP News & Updates
Latest from PrEP Committee
Lots of news from the PreP Committee!
Slides from the last PrEP Committee meeting, held on October 28, appear below. The agenda included a presentation by Jonathan Volk on Kaiser PrEP data and a presentation by the NURX.co team about their PrEP delivery model. Also, a manuscript has just been published in JAMA Internal Medicine describing results from the SF Department of Public Health’s PrEP…
How Some US Doctors Are Hindering HIV Prevention
Jake Mason will never forget the response he received when he asked for a Truvada prescription to prevent HIV at a clinic in Los Angeles. “The first thing the doctor said was ‘Why do you want to be a cum dumpster?’” Mason alleged, adding that he couldn’t remember the doctor’s name. “He said, ‘Well, I…
Project Inform Launches Report on PrEP Access in California
Project Inform has published a report entitled “Scaling Up Pre-Exposure Prophylaxis in California” laying out recommendations for increasing access to and uptake of HIV pre-exposure prophylaxis (PrEP) in the state of California. The report comes from a think tank held in November 2014, attended by over 50 stakeholders from government, academia, public health departments, medical…
First-of-Its-Kind Lawsuit from Gay Man Denied Insurance Because He’s on PrEP
Earlier this week, the Gay & Lesbian Advocates & Defenders (GLAD, not to be confused with GLAAD) filed a claim with the Massachusetts Commission Against Discrimination charging that Mutual of Omaha Insurance Company discriminated against a gay man when they denied him long-term care insurance because he’s taking Truvada as PrEP. This is the first…