Staying informed and accessing resources for HIV prevention is crucial. If you’re considering PrEP (Pre-Exposure Prophylaxis), San Francisco has numerous accessible services.
About PrEP & Comparing Options

About PrEP as a pill: daily – SFDPH
Taking PrEP as a daily pill protects you from HIV when having any type of sex. PrEP is safe and can reduce your risk of HIV by more than 99%.
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About PrEP as a pill: 2-1-1 – SFDPH
2-1-1 PrEP means taking PrEP pills only on the days when you have sex, and for 2 days after. You must follow a specific schedule of pills correctly for it to work. Truvada is the only PrEP pill you can take on the 2-1-1 schedule.
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Compare your options for PrEP/Compare sus opciones para PrEP – SFDPH
Table comparing four FDA-approved medications for PrEP – Yeztugo, Apretude, Truvada, Descovy. Existen 4 medicamentos aprobados por la FDA para PrEP. Todos son seguros y altamente efectivos cuando se toman según las indicaciones.

Which PrEP medication is best for me?/¿Cuál es el mejor medicamento PrEP para mí? – SFAF
There are four FDA-approved PrEP medications: Truvada, Descovy, Apretude, and Yeztugo. This table compares them.
About Injectable PrEP & Where to find it in SF

About injectable PrEP: cabotegravir/Acerca de la PrEP inyectable (Apretude)
One-page overview of long-acting injectable cabotegravir for PrEP developed by SFDPH

About injectable PrEP: lenacapavir/Acerca de la PrEP inyectable (Yeztugo)
One-page overview of long-acting injectable lenacapvir for PrEP developed by SFDPH

Sites Offering Long-Acting Injectables
List of clinics & providers that provide LAIs for prevention & treatment
Youth

Healthcare for youth ages 12-24
List of 10 clinics that provide a variety of medical services for San Francisco youth with a special commitment to uninsured, low-income and medically underserved families


